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Complete Biomarker Taxonomy

The BSP Taxonomy is the universal language for measuring biological state. It currently contains 210+ approved biomarkers divided into 25 categories and 4 access levels.

NOTE

This is a living standard. New biomarkers are added quarterly via the BIP Governance Process.

1. Core Longevity (BSP-LA)

The primary markers used by the AVA engine to determine the Ambrósio Vitality Score (SVA).

CodeBiomarkerUnitExpected Optimal RangeMethod
BSP-LA-001High-Sensitivity CRP (hs-CRP)mg/L< 0.5Immunoassay
BSP-LA-002Fasting InsulinµIU/mL2.0 - 5.0ECLIA
BSP-LA-003Homocysteineµmol/L5.0 - 7.0HPLC
BSP-LA-004HbA1c%4.6 - 5.0HPLC
BSP-LA-005Free Testosteroneng/dLAge/Sex dependentLC-MS/MS
BSP-LA-006Vitamin D (25-OH)ng/mL50.0 - 80.0LC-MS/MS
BSP-LA-007Omega-3 Index%> 8.0GC-MS
BSP-LA-008ApoBmg/dL< 60Immunoturbidimetry
BSP-LA-009NAD+ / NADH Ratioratio> 400LC-MS

2. Essential Metabolism (BSP-MT)

Markers for assessing metabolic flexibility, mitochondrial function, and energy substrates.

CodeBiomarkerUnitExpected Optimal RangeMethod
BSP-MT-001Fasting Glucosemg/dL75 - 85Hexokinase
BSP-MT-002Uric Acidmg/dL3.5 - 5.0Uricase
BSP-MT-003Lactate Dehydrogenase (LDH)U/L140 - 200UV Kinetic
BSP-MT-004Ferritinng/mL50 - 150ECLIA
BSP-MT-005Triglyceridesmg/dL< 70Enzymatic

3. Cardiovascular Dynamics (BSP-CV)

Advanced lipidology, endothelial function, and vascular health.

CodeBiomarkerUnitExpected Optimal RangeMethod
BSP-CV-001LDL Particle Number (LDL-P)nmol/L< 1000NMR
BSP-CV-002Lipoprotein(a)mg/dL< 14Immunoturbidimetry
BSP-CV-003Fibrinogenmg/dL200 - 300Clauss
BSP-CV-004Oxidized LDLU/L< 45ELISA

4. Device & Wearables Continuously Tracked (BSP-DV)

Data collected continuously from BSP-certified consumer and clinical hardware (Oura, Apple Watch, WHOOP).

CodeBiomarkerUnitFrequencyMethod
BSP-DV-001Resting Heart Rate (RHR)bpmDaily AvgPPG / ECG
BSP-DV-002Heart Rate Variability (HRV)ms (RMSSD)Daily AvgPPG / ECG
BSP-DV-003Slow Wave Sleep DurationminNightlyActigraphy + Temp
BSP-DV-004REM Sleep DurationminNightlyActigraphy + Temp
BSP-DV-005Nocturnal Body Temp Deviation°CNightlyThermistor
BSP-DV-006VO2 Max EstimatemL/kg/minMonthlyMultisensor model

For the complete JSON list of all 210+ biomarkers to integrate into your application, see the bsp-spec repository.